GPIHBP1

Across TCGA patient cohorts, GPIHBP1 mutation is significantly associated with the RNA expression of many other genes, with 99 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GPIHBP1-associated genes across cancer lineages are BANF1P5, RN7SKP282, and MIR5583-1. Each is linked with GPIHBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPIHBP1-to-partner and partner-to-GPIHBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BANF1P5 grouped by GPIHBP1-low versus GPIHBP1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPIHBP1→partner) and Y-score (partner→GPIHBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BANF1P5 →	+0.192	+4.584	.004	.001	3	2
LUSC	RN7SKP282 →	+0.184	+5.038	<.001	.009	3	2
LUSC	MIR5583-1 →	+0.691	+5.038	<.001	.009	3	2
COAD	RNA5SP239 →	+0.623	+7.741	<.001	.009	3	2
COAD	RN7SL722P →	+0.134	+7.741	<.001	.009	3	2
UCEC	NPAP1P2 →	+0.067	+3.701	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

BANF1P5 by GPIHBP1 expression — LUAD

Explore this box plot interactively →