GPC5

Across TCGA patient cohorts, GPC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,189 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPC5-associated proteins across cancer lineages are DDAH1, INPP4A, and MYEF2. Each is linked with GPC5 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPC5-to-partner and partner-to-GPC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPC5 versus DDAH1 in LSCC, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC5→partner) and Y-score (partner→GPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDAH1 →	+0.544	+0.574	<.001	.004	3	4
HNSC	INPP4A →	+0.245	+0.535	<.001	.001	3	4
HNSC	MYEF2 →	+0.863	+0.543	<.001	.003	3	3
HNSC	MYO1E →	-0.258	-0.289	<.001	.004	3	3
UCEC	PARP1 →	+0.386	+0.440	<.001	.001	2	4
GBM	PLCB1 →	+0.538	+1.009	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,189 associations by consensus.

GPC5 vs DDAH1 — LSCC

Explore this scatter interactively →