GPC5

Across TCGA patient cohorts, GPC5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,273 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPC5-associated genes across cancer lineages are PRODH, SOX10, and RASL10A. Each is linked with GPC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPC5-to-partner and partner-to-GPC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPC5 versus PRODH in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC5→partner) and Y-score (partner→GPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.891	+0.696	<.001	<.001	3	1
GBM	SOX10 →	+1.445	+0.651	.001	<.001	3	1
GBM	RASL10A →	+0.649	+0.527	.008	.004	3	1
GBM	NEFH →	+0.899	+0.549	<.001	<.001	3	1
GBM	RASD2 →	+0.407	+0.386	.001	.009	3	1
GBM	SYNGR1 →	+0.805	+0.666	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,273 associations by consensus.

GPC5 vs PRODH — GBM

Explore this scatter interactively →