GPC5

Across TCGA cell cohorts, GPC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 790 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPC5-associated GO terms across cancer lineages are Aerobic respiration, Potassium ion transmembrane transport, and Protein deneddylation. Each is linked with GPC5 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPC5-to-partner and partner-to-GPC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by GPC5-low versus GPC5-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC5→partner) and Y-score (partner→GPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Aerobic respiration →	+0.063	+0.369	<.001	.008	3	6
OVARY	Potassium ion transmembrane transport →	-0.072	-0.524	<.001	<.001	3	6
OVARY	Protein deneddylation →	+0.096	+0.899	<.001	.007	3	6
BLOOD_Lymphoma	Translational initiation →	+0.054	+0.421	.004	.005	3	5
SKIN	Regulation of sodium ion transmembrane transporter activity →	-0.195	-0.591	<.001	.008	3	5
SKIN	Positive regulation of sodium ion transmembrane transporter activity →	-0.125	-0.458	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 790 associations by consensus.

Aerobic respiration by GPC5 expression — BLOOD_Leukemia

Explore this box plot interactively →