Across TCGA patient cohorts, GPATCH8 protein abundance is significantly associated with the RNA expression of many other genes, with 14,875 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPATCH8-associated genes across cancer lineages are RFC5, MBTD1, and KIF14. Each is linked with GPATCH8 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPATCH8-to-partner and partner-to-GPATCH8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH8→partner) and Y-score (partner→GPATCH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC5 →	+0.731	+0.188	<.001	<.001	3	6
HNSC	MBTD1 →	+0.802	+0.187	<.001	<.001	3	6
GBM	KIF14 →	+1.080	+0.282	<.001	<.001	3	6
HNSC	HELLS →	+0.778	+0.186	<.001	<.001	3	6
HNSC	TOP2A →	+1.293	+0.205	.001	<.001	3	6
HNSC	PTCD3 →	+0.794	+0.209	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,875 associations by consensus.

Exploration

GPATCH8 survival (RNA) · tumor vs normal (RNA) · all GPATCH8 data types