GPATCH2L

Across TCGA patient cohorts, GPATCH2L mutation is significantly associated with the RNA expression of many other genes, with 2,874 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPATCH2L-associated genes across cancer lineages are RNU6-1126P, OR4G6P, and RNU6-855P. Each is linked with GPATCH2L in more than 2 cancer types. Because this analysis shows association rather than direction, both GPATCH2L-to-partner and partner-to-GPATCH2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1126P grouped by GPATCH2L-low versus GPATCH2L-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH2L→partner) and Y-score (partner→GPATCH2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1126P →	+0.265	+5.444	<.001	.002	3	3
BLCA	OR4G6P →	+0.044	+7.640	<.001	.009	3	2
LUSC	RNU6-855P →	+0.437	+5.474	<.001	.005	3	2
LUAD	RNA5SP158 →	+0.470	+4.631	<.001	.008	3	2
LUAD	RNA5SP146 →	+0.419	+4.787	<.001	.003	3	2
UCEC	RN7SKP59 →	+0.059	+2.051	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,874 associations by consensus.

RNU6-1126P by GPATCH2L expression — LUAD

Explore this box plot interactively →