GP9

Across TCGA patient cohorts, GP9 mutation is significantly associated with the RNA expression of many other genes, with 79 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GP9-associated genes across cancer lineages are OR52K1, MIR185, and TTTY2. Each is linked with GP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both GP9-to-partner and partner-to-GP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52K1 grouped by GP9-low versus GP9-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GP9→partner) and Y-score (partner→GP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR52K1 →	+0.058	+4.588	<.001	.008	3	2
BLCA	MIR185 →	+0.513	+4.883	<.001	.002	3	2
LUSC	TTTY2 →	+0.009	+7.924	<.001	.008	3	2
BLCA	SNORA70D →	+0.279	+4.685	<.001	.007	3	1
BLCA	MIR4286 →	+1.000	+4.463	<.001	.005	3	1
BLCA	MIR3617 →	+0.367	+4.685	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

OR52K1 by GP9 expression — BLCA

Explore this box plot interactively →