Q-omics provides the consensus-scored MIR185 profile across patient tissues and cancer cell-line models. MIR185 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, MIR185 is differentially expressed in 2, with the highest sampling consensus in KICH. Additionally, MIR185 RNA expression shows 7,584 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight BLCA, KICH, and DLBC as cancer lineages where MIR185 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR185 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR185 survival associations across molecular data types. MIR185 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR185 RNA expression–survival associations across cancer types. High MIR185 expression shows unfavorable associations in BLCA, UCEC, ACC and LGG, but favorable associations in SKCM and LUAD. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify BLCA as the clearest survival context for MIR185 RNA expression.
This table summarizes MIR185 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for MIR185. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR185 shows higher tumor expression in KICH and BRCA. The KICH box plot shows higher MIR185 RNA expression in tumor versus normal tissue (log2 FC = +0.416, t-test p < 0.001).
This table shows molecular features associated with MIR185 in patient tissues and cancer cell lines. In patient samples, MIR185 shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
