Across TCGA patient cohorts, GP1BB mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GP1BB-associated genes across cancer lineages are MIR4507, MIR548AK, and RN7SKP224. Each is linked with GP1BB in more than 1 cancer types. Because this analysis shows association rather than direction, both GP1BB-to-partner and partner-to-GP1BB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GP1BB→partner) and Y-score (partner→GP1BB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4507 →	+0.958	+5.420	<.001	.005	3	1
UCEC	MIR548AK →	+1.042	+5.551	<.001	.004	3	1
UCEC	RN7SKP224 →	+0.281	+5.133	.002	.008	3	1
UCEC	RNU6-12P →	+0.439	+5.299	.005	.006	3	1
UCEC	SC4MOP →	+0.153	+6.453	<.001	.001	3	1
UCEC	CHEK2P5 →	+0.361	+5.358	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

GP1BB survival (RNA) · tumor vs normal (RNA) · all GP1BB data types