GOLT1A

Across TCGA cell cohorts, GOLT1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,515 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GOLT1A-associated GO terms across cancer lineages are Cytoplasmic actin-based contraction involved in cell motility, Acetylcholine biosynthetic process, and Calcium-independent cell-cell adhesion. Each is linked with GOLT1A in more than 8 cancer types. Because this analysis shows association rather than direction, both GOLT1A-to-partner and partner-to-GOLT1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic actin-based contraction involved in cell motility grouped by GOLT1A-low versus GOLT1A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLT1A→partner) and Y-score (partner→GOLT1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cytoplasmic actin-based contraction involved in cell motility →	+0.450	+1.507	.001	<.001	3	8
OESOPHAGUS	Acetylcholine biosynthetic process →	+1.424	+2.739	<.001	<.001	3	8
BREAST	Calcium-independent cell-cell adhesion →	+0.313	+1.807	.007	.001	3	8
LIVER	Positive regulation of endothelial cell development →	+0.280	+2.865	<.001	<.001	3	8
LIVER	Positive regulation of establishment of endothelial barrier →	+0.280	+2.865	<.001	<.001	3	8
STOMACH	Protein transport within lipid bilayer →	+0.338	+1.719	.005	.007	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,515 associations by consensus.

Cytoplasmic actin-based contraction involved in cell motility by GOLT1A expression — BREAST

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