GOLM2

Across TCGA patient cohorts, GOLM2 mutation is significantly associated with the RNA expression of many other genes, with 1,343 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLM2-associated genes across cancer lineages are MARK2P4, RN7SL248P, and RNA5SP412. Each is linked with GOLM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLM2-to-partner and partner-to-GOLM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MARK2P4 grouped by GOLM2-low versus GOLM2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLM2→partner) and Y-score (partner→GOLM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MARK2P4 →	+0.029	+6.144	<.001	.001	3	2
UCEC	RN7SL248P →	+0.051	+2.783	<.001	.009	3	2
UCEC	RNA5SP412 →	+0.713	+2.289	<.001	<.001	3	2
UCEC	RNVU1-28 →	+0.915	+2.082	<.001	<.001	3	2
SKCM	AQP7P5 →	+0.175	+3.395	<.001	.002	3	2
UCEC	ZDHHC7 →	+0.370	+2.639	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,343 associations by consensus.

MARK2P4 by GOLM2 expression — CESC

Explore this box plot interactively →