GOLGA8IP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA8IP mutation is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA8IP-associated genes across cancer lineages are OR7E97P, AQP7P2, and LUADT1. Each is linked with GOLGA8IP in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8IP-to-partner and partner-to-GOLGA8IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E97P grouped by GOLGA8IP-low versus GOLGA8IP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8IP→partner) and Y-score (partner→GOLGA8IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOR7E97P →+0.198+4.877<.001.00331
UCECAQP7P2 →+0.298+4.332<.001.00131
UCECLUADT1 →+0.360+3.603<.001.00431
UCECTEX43 →+0.710+3.858<.001.00431
UCECIFNL3 →+0.354+3.653.006.00831
UCECMIR365A →+0.752+3.889<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

OR7E97P by GOLGA8IP expression — UCEC

Box plot of OR7E97P in GOLGA8IP-low vs GOLGA8IP-high samples in UCEC.

Explore this box plot interactively →

Exploration