GOLGA8IP

Across TCGA pan-cancer cohorts, GOLGA8IP RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of GOLGA8IP’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GOLGA8IP RNA is repressed in tumor relative to normal tissue. In most cancer types GOLGA8IP is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and UCEC are the cancer types where GOLGA8IP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOLGA8IP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.330	<.001	8	view →
BRCA	All	All	−0.119	<.001	6	view →
UCEC	All	All	−0.068	<.001	6	view →
KIRC	All	All	+0.129	.008	5	view →
LUSC	All	All	−0.047	<.001	5	view →
LUAD	All	All	−0.032	.033	3	view →
LIHC	Female	All	+0.035	.035	2	view →
BLCA	Male	IV	−0.090	.032	1	view →
READ	All	All	−0.038	.039	1	view →
COAD	Female	III,IV	−0.016	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

GOLGA8IP–THCA

Open the THCA breakdown →