GOLGA8IP

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA8IP mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8IP-associated genes across cancer lineages are SERPINA4, CFHR5, and FERD3L. Each is linked with GOLGA8IP in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8IP-to-partner and partner-to-GOLGA8IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA4 grouped by GOLGA8IP-low versus GOLGA8IP-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8IP→partner) and Y-score (partner→GOLGA8IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaSERPINA4 →+0.011+5.507<.001<.00131
BLOOD_LeukemiaCFHR5 →+0.004+4.969<.001.00331
BLOOD_LeukemiaFERD3L →+0.034+4.969<.001.00331
BLOOD_LeukemiaHTR1E →+0.004+4.969<.001.00331
BLOOD_LeukemiaC11orf97 →+0.046+4.409.004.00531
BLOOD_LeukemiaSPANXN2 →+0.025+5.060<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

SERPINA4 by GOLGA8IP expression — BLOOD_Leukemia

Box plot of SERPINA4 in GOLGA8IP-low vs GOLGA8IP-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration