GOLGA8H

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA8H mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8H-associated genes across cancer lineages are BPIFA2, USP17L8, and TEX51. Each is linked with GOLGA8H in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8H-to-partner and partner-to-GOLGA8H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFA2 grouped by GOLGA8H-low versus GOLGA8H-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8H→partner) and Y-score (partner→GOLGA8H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaBPIFA2 →+0.009+3.969.007.00931
BLOOD_LeukemiaUSP17L8 →+0.003+3.969<.001.00931
BLOOD_LeukemiaTEX51 →+0.286+3.969<.001.00931
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

BPIFA2 by GOLGA8H expression — BLOOD_Leukemia

Box plot of BPIFA2 in GOLGA8H-low vs GOLGA8H-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration