GOLGA8H

Across TCGA pan-cancer cohorts, GOLGA8H RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of GOLGA8H’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GOLGA8H RNA is repressed in tumor relative to normal tissue. In most cancer types GOLGA8H is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and BLCA are the cancer types where GOLGA8H tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOLGA8H RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.513	<.001	8	view →
BRCA	All	III,IV	−0.422	<.001	6	view →
BLCA	Male	IV	−0.537	.005	5	view →
CHOL	All	II,III,IV	+0.345	.009	4	view →
LIHC	All	All	+0.064	<.001	4	view →
LUSC	All	All	−0.149	.007	3	view →
LUAD	Female	II,III,IV	−0.199	.012	2	view →
HNSC	Female	All	+0.129	.019	2	view →
COAD	Female	II,III,IV	−0.118	.011	2	view →
KICH	Male	All	−0.253	.019	1	view →
HNSC	Male	All	−0.081	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

GOLGA8H–THCA

Open the THCA breakdown →