GOLGA6D

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA6D mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA6D-associated genes across cancer lineages are OR10G7, KRTAP23-1, and FSCB. Each is linked with GOLGA6D in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6D-to-partner and partner-to-GOLGA6D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G7 grouped by GOLGA6D-low versus GOLGA6D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6D→partner) and Y-score (partner→GOLGA6D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOR10G7 →+0.085+4.538<.001.00631
UCECKRTAP23-1 →+0.537+4.302<.001.00231
UCECFSCB →+0.093+4.026<.001.00631
UCECOR6M1 →+0.173+4.413.008.00231
UCECRNU6-170P →+0.494+5.292<.001.00231
UCECRNU6-271P →+0.538+4.267<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

OR10G7 by GOLGA6D expression — UCEC

Box plot of OR10G7 in GOLGA6D-low vs GOLGA6D-high samples in UCEC.

Explore this box plot interactively →

Exploration