GOLGA6A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA6A mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GOLGA6A-associated genes across cancer lineages are RNU6-905P, TRIM64DP, and OR5L2. Each is linked with GOLGA6A in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6A-to-partner and partner-to-GOLGA6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-905P grouped by GOLGA6A-low versus GOLGA6A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6A→partner) and Y-score (partner→GOLGA6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-905P →+0.462+5.885<.001.00132
SKCMTRIM64DP →+0.043+5.797<.001.00132
LUADOR5L2 →+0.034+7.930<.001.00831
LUADAARS1P1 →+0.069+7.930<.001.00831
LUADSNRPGP16 →+0.223+7.930<.001.00831
LUADOR10AF1P →+0.069+7.930<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

RNU6-905P by GOLGA6A expression — UCEC

Box plot of RNU6-905P in GOLGA6A-low vs GOLGA6A-high samples in UCEC.

Explore this box plot interactively →

Exploration