GOLGA6A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA6A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GOLGA6A-associated genes across cancer lineages are SOX14 and GSG1L2. Each is linked with GOLGA6A in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6A-to-partner and partner-to-GOLGA6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SOX14 grouped by GOLGA6A-low versus GOLGA6A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6A→partner) and Y-score (partner→GOLGA6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaSOX14 →+0.012+4.867<.001.00931
BLOOD_LymphomaGSG1L2 →+0.073+6.247<.001<.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SOX14 by GOLGA6A expression — BLOOD_Lymphoma

Box plot of SOX14 in GOLGA6A-low vs GOLGA6A-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration