GNMT

Across TCGA patient cohorts, GNMT protein abundance is significantly associated with the RNA expression of many other genes, with 4,575 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNMT-associated genes across cancer lineages are MTFMT, TNPO2, and TMEM97. Each is linked with GNMT in more than 1 cancer types. Because this analysis shows association rather than direction, both GNMT-to-partner and partner-to-GNMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNMT versus MTFMT in HNSC, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNMT→partner) and Y-score (partner→GNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MTFMT →	-0.755	-0.922	.004	.008	3	2
HNSC	TNPO2 →	-0.857	-0.990	.004	.005	3	2
HNSC	TMEM97 →	-1.653	-1.033	.001	.008	3	2
HNSC	PYCR2 →	-1.247	-1.020	.001	.005	3	2
HNSC	CCDC183-AS1 →	-0.980	-0.923	.003	.005	3	2
HNSC	TMEM161B-AS1 →	-1.442	-0.911	.008	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,575 associations by consensus.

GNMT vs MTFMT — HNSC

Explore this scatter interactively →