Q-omics provides the consensus-scored TMEM161B-AS1 profile across patient tissues and cancer cell-line models. TMEM161B-AS1 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, TMEM161B-AS1 is differentially expressed in 10, with the highest sampling consensus in LIHC. Additionally, TMEM161B-AS1 RNA expression shows 19,052 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KICH, LIHC, and UVM as cancer lineages where TMEM161B-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TMEM161B-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TMEM161B-AS1 survival associations across molecular data types. TMEM161B-AS1 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TMEM161B-AS1 RNA expression–survival associations across cancer types. High TMEM161B-AS1 expression shows unfavorable associations in KICH, ACC, OV, UVM and LIHC, but favorable associations in KIRP. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KICH as the clearest survival context for TMEM161B-AS1 RNA expression.
This table summarizes TMEM161B-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in LIHC for RNA.
This table ranks reproducible tumor–normal expression differences for TMEM161B-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TMEM161B-AS1 shows lower tumor expression in KICH, BRCA, ESCA and THCA and higher tumor expression in LIHC and CHOL. The LIHC box plot shows higher TMEM161B-AS1 RNA expression in tumor versus normal tissue (log2 FC = +0.890, t-test p < 0.001).
This table shows molecular features associated with TMEM161B-AS1 in patient tissues and cancer cell lines. In patient samples, TMEM161B-AS1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
