GNAZ

Across TCGA patient cohorts, GNAZ RNA expression is significantly associated with the protein abundance of many other proteins, with 20,169 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNAZ-associated proteins across cancer lineages are SQOR, KIF1A_S1370, and SUGP2. Each is linked with GNAZ in more than 5 cancer types. Because this analysis shows association rather than direction, both GNAZ-to-partner and partner-to-GNAZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAZ versus SQOR in GBM, with a Pearson correlation of -0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAZ→partner) and Y-score (partner→GNAZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SQOR →	-0.565	-0.532	<.001	<.001	3	6
LSCC	KIF1A_S1370 →	+2.323	+1.196	<.001	<.001	3	6
OV	SUGP2 →	+0.352	+0.652	.003	.006	3	6
LSCC	MYEF2 →	+0.867	+1.058	<.001	<.001	3	5
GBM	SEPTIN3 →	+0.693	+0.883	<.001	<.001	3	5
LSCC	CASP4 →	-0.500	-1.220	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,169 associations by consensus.

GNAZ vs SQOR — GBM

Explore this scatter interactively →