GNAZ

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GNAZ protein abundance is significantly associated with the RNA expression of many other genes, with 9,762 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNAZ-associated genes across cancer lineages are KIAA1549, OR52D1, and UNC13A. Each is linked with GNAZ in more than 2 cancer types. Because this analysis shows association rather than direction, both GNAZ-to-partner and partner-to-GNAZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAZ versus KIAA1549 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAZ→partner) and Y-score (partner→GNAZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCKIAA1549 →+1.180+0.631.003.00633
PDACOR52D1 →+0.805+0.811<.001<.00133
GBMUNC13A →+1.178+0.822<.001<.00132
GBMSYN2 →+1.974+0.889<.001<.00132
CCRCCSPATA2 →+0.544+0.432.007.00632
CCRCCPRELID1P1 →+0.467+0.432.007.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,762 associations by consensus.

GNAZ vs KIAA1549 — LSCC

Per-sample scatter of GNAZ vs KIAA1549 in LSCC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration