GNAZ

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GNAZ RNA expression is significantly associated with the go_rna of many other GO terms, with 4,941 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GNAZ-associated GO terms across cancer lineages are Nucleosome organization, Positive regulation of double-strand break repair, and Positive regulation of DNA repair. Each is linked with GNAZ in more than 13 cancer types. Because this analysis shows association rather than direction, both GNAZ-to-partner and partner-to-GNAZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome organization grouped by GNAZ-low versus GNAZ-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAZ→partner) and Y-score (partner→GNAZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENucleosome organization →+0.105+0.968<.001.006314
OVARYPositive regulation of double-strand break repair →+0.083+1.387<.001<.001313
LUNG_SCLCPositive regulation of DNA repair →+0.063+1.615.002<.001313
OESOPHAGUSPurine nucleoside triphosphate biosynthetic process →+0.099+1.162.001<.001313
OESOPHAGUSPurine ribonucleoside triphosphate biosynthetic process →+0.099+1.162.001<.001313
OVARYPositive regulation of double-strand break repair via homologous recombination →+0.069+1.099<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,941 associations by consensus.

Nucleosome organization by GNAZ expression — BONE

Box plot of Nucleosome organization in GNAZ-low vs GNAZ-high samples in BONE.

Explore this box plot interactively →

Exploration