GNAI1

Across TCGA patient cohorts, GNAI1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,390 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNAI1-associated proteins across cancer lineages are APBB2, SYDE1, and ZNF592_S348. Each is linked with GNAI1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GNAI1-to-partner and partner-to-GNAI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAI1 versus APBB2 in PDAC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAI1→partner) and Y-score (partner→GNAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	APBB2 →	+0.389	+0.307	<.001	.001	3	5
PDAC	SYDE1 →	+0.300	+0.270	.004	.007	3	5
BRCA	ZNF592_S348 →	-0.500	-0.635	<.001	<.001	3	5
GBM	CENPC_S709 →	-0.571	-1.164	.001	<.001	3	5
BRCA	BST2 →	-0.901	-0.741	<.001	<.001	3	5
OV	SERPINA4 →	+0.692	+0.648	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,390 associations by consensus.

GNAI1 vs APBB2 — PDAC

Explore this scatter interactively →