GMPS

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GMPS RNA expression is significantly associated with the protein abundance of many other proteins, with 24,053 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GMPS-associated proteins across cancer lineages are MCM3, MCM4, and MCM7. Each is linked with GMPS in more than 8 cancer types. Because this analysis shows association rather than direction, both GMPS-to-partner and partner-to-GMPS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMPS versus MCM3 in LUAD, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPS→partner) and Y-score (partner→GMPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADMCM3 →+0.715+0.404<.001<.00139
LUADMCM4 →+0.737+0.405<.001<.00139
LUADMCM7 →+0.731+0.405<.001<.00139
LSCCFXR1 →+0.519+1.040<.001<.00139
BRCAHAT1 →+0.405+0.490<.001<.00139
LSCCRFC2 →+0.452+0.910<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 24,053 associations by consensus.

GMPS vs MCM3 — LUAD

Per-sample scatter of GMPS vs MCM3 in LUAD (Pearson r = 0.55).

Explore this scatter interactively →

Exploration