GMNN

Across TCGA cell cohorts, GMNN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,430 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GMNN-associated GO terms across cancer lineages are Mitotic DNA replication checkpoint signaling, Negative regulation of RNA export from nucleus, and DNA-templated DNA replication. Each is linked with GMNN in more than 18 cancer types. Because this analysis shows association rather than direction, both GMNN-to-partner and partner-to-GMNN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA replication checkpoint signaling grouped by GMNN-low versus GMNN-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMNN→partner) and Y-score (partner→GMNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Mitotic DNA replication checkpoint signaling →	+0.164	+0.972	<.001	<.001	3	19
LIVER	Negative regulation of RNA export from nucleus →	+0.154	+1.045	<.001	.001	3	19
BONE	DNA-templated DNA replication →	+0.164	+1.186	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.253	+1.709	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.144	+1.235	<.001	<.001	3	19
SOFT_TISSUE	Positive regulation of chromosome condensation →	+0.240	+1.285	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,430 associations by consensus.

Mitotic DNA replication checkpoint signaling by GMNN expression — KIDNEY

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