GML

Across TCGA patient cohorts, GML mutation is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GML-associated genes across cancer lineages are TCERG1L-AS1, RNA5SP243, and MIR6780B. Each is linked with GML in more than 1 cancer types. Because this analysis shows association rather than direction, both GML-to-partner and partner-to-GML results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCERG1L-AS1 grouped by GML-low versus GML-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GML→partner) and Y-score (partner→GML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TCERG1L-AS1 →	+0.432	+3.133	<.001	.001	3	2
SKCM	RNA5SP243 →	+0.696	+3.072	.001	<.001	3	2
SKCM	MIR6780B →	+0.281	+2.448	.009	.008	3	2
STAD	RNA5SP333 →	+0.331	+4.798	<.001	.006	3	2
SKCM	CNTNAP3P1 →	+0.098	+2.482	<.001	.005	3	1
UCEC	MIR7973-1 →	+0.413	+3.136	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

TCERG1L-AS1 by GML expression — UCEC

Explore this box plot interactively →