GML

Across TCGA pan-cancer cohorts, GML RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GML’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GML RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GML is over-expressed in tumor.

KIRC, HNSC, and BRCA are the cancer types where GML tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GML RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.010	.016	3	view →
HNSC	Female	II,III,IV	+0.036	.036	2	view →
BRCA	All	III,IV	+0.029	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

GML–KIRC

Open the KIRC breakdown →