GLUD1

Across TCGA patient cohorts, GLUD1 mutation is significantly associated with the RNA expression of many other genes, with 1,142 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLUD1-associated genes across cancer lineages are RNA5SP478, H3P46, and PTCD2P1. Each is linked with GLUD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLUD1-to-partner and partner-to-GLUD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP478 grouped by GLUD1-low versus GLUD1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLUD1→partner) and Y-score (partner→GLUD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP478 →	+0.322	+4.314	<.001	.009	3	3
BRCA	H3P46 →	+0.088	+7.731	<.001	.009	3	2
LUSC	PTCD2P1 →	+0.049	+4.993	.004	.003	3	2
SKCM	RNU1-49P →	+0.645	+5.993	<.001	.001	3	2
BRCA	RNU6-290P →	+0.402	+7.731	<.001	.009	3	2
SKCM	TAS2R41 →	+0.036	+4.680	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,142 associations by consensus.

RNA5SP478 by GLUD1 expression — BLCA

Explore this box plot interactively →