GLT8D2

Across TCGA patient cohorts, GLT8D2 mutation is significantly associated with the RNA expression of many other genes, with 772 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLT8D2-associated genes across cancer lineages are RNU6-1126P, RNU6-375P, and SNORD116-7. Each is linked with GLT8D2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLT8D2-to-partner and partner-to-GLT8D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1126P grouped by GLT8D2-low versus GLT8D2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLT8D2→partner) and Y-score (partner→GLT8D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1126P →	+0.215	+4.122	<.001	.009	3	3
READ	RNU6-375P →	+0.598	+4.445	<.001	.005	3	2
SKCM	SNORD116-7 →	+0.332	+2.126	<.001	.008	3	2
LUAD	RNA5SP176 →	+0.211	+5.602	<.001	.001	3	2
GBM	RNU6-1241P →	+0.394	+4.969	<.001	.009	3	2
LUSC	FAM96AP1 →	+0.072	+4.993	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 772 associations by consensus.

RNU6-1126P by GLT8D2 expression — LUAD

Explore this box plot interactively →