GLT8D2

Across TCGA pan-cancer cohorts, GLT8D2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated GLT8D2 data layer compared with 7 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher GLT8D2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GLT8D2 expression acts as an unfavorable survival marker, although some lineages such as COAD and LIHC show a favorable association.

KIRP, MESO, and STAD are the cancer types where GLT8D2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.318	0.687	<.001	115	view →
MESO	OS	Median	II,III,IV	0.192	0.388	.002	56	view →
STAD	OS	Quartile	All	0.500	0.677	.002	41	view →
CESC	DFS	Tertile	All	0.709	0.852	.002	36	view →
BLCA	OS	Median	All	0.556	0.665	.011	34	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	31	view →
THCA	OS	Median	III,IV	0.945	1.000	.004	24	view →
COAD	OS	Quartile	III,IV	0.901	0.595	.011	14	view →
LIHC	DFS	Median	III,IV	0.547	0.247	.009	13	view →
DLBC	DFS	Median	III,IV	1.000	0.525	.013	8	view →
SKCM	OS	Quartile	III,IV	0.747	0.535	.027	6	view →
ACC	DFS	Tertile	IV	0.048	0.396	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

GLT8D2–KIRP (DFS)

Open the KIRP breakdown →