Across TCGA patient cohorts, GLRX5 mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLRX5-associated genes across cancer lineages are RNA5SP389, SNRPGP1, and MIR6842. Each is linked with GLRX5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLRX5-to-partner and partner-to-GLRX5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX5→partner) and Y-score (partner→GLRX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP389 →	+0.651	+3.294	.001	.007	3	2
BLCA	SNRPGP1 →	+0.203	+5.106	<.001	.008	3	1
BLCA	MIR6842 →	+0.604	+5.177	<.001	.007	3	1
UCEC	RNA5SP414 →	+0.988	+3.255	<.001	.003	3	1
UCEC	RNA5SP412 →	+1.021	+3.704	<.001	<.001	3	1
UCEC	IGHV1OR21-1 →	+0.968	+3.784	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

Exploration

GLRX5 survival (RNA) · tumor vs normal (RNA) · all GLRX5 data types