GLRA4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GLRA4 mutation is significantly associated with the RNA expression of many other genes, with 2,164 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLRA4-associated genes across cancer lineages are RN7SL248P, SAR1B, and EOMES. Each is linked with GLRA4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLRA4-to-partner and partner-to-GLRA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRA4→partner) and Y-score (partner→GLRA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.055+3.022<.001.00133
UCECSAR1B →+0.456+2.321<.001<.00132
UCECEOMES →+0.466+2.687<.001<.00132
UCECZMAT1 →-0.497-1.716.009.00432
UCECPHOSPHO1 →-0.415-2.055.007.00532
UCECLSM1 →+0.406+3.743.005<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,164 associations by consensus.

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