GLO1

Across TCGA patient cohorts, GLO1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,586 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GLO1-associated genes across cancer lineages are FAM8A1, RNF5, and GPANK1. Each is linked with GLO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GLO1-to-partner and partner-to-GLO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLO1 versus FAM8A1 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLO1→partner) and Y-score (partner→GLO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM8A1 →	+0.609	+0.329	<.001	<.001	3	6
CCRCC	RNF5 →	+0.667	+0.294	<.001	<.001	3	6
OV	GPANK1 →	+0.558	+0.775	<.001	<.001	3	6
OV	RGL2 →	+0.632	+0.634	<.001	<.001	3	6
BRCA	PREPL →	+0.512	+0.313	.003	.005	3	5
BRCA	ZNF181 →	+0.678	+0.502	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,586 associations by consensus.

GLO1 vs FAM8A1 — BRCA

Explore this scatter interactively →