GLIPR2

Across TCGA patient cohorts, GLIPR2 mutation is significantly associated with the RNA expression of many other genes, with 609 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLIPR2-associated genes across cancer lineages are ZNF280B, MIR6500, and STMN1P1. Each is linked with GLIPR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLIPR2-to-partner and partner-to-GLIPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF280B grouped by GLIPR2-low versus GLIPR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR2→partner) and Y-score (partner→GLIPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF280B →	+0.592	+2.711	.001	.003	3	1
UCEC	MIR6500 →	+0.255	+2.674	.006	.006	3	1
UCEC	STMN1P1 →	+0.469	+2.711	<.001	.003	3	1
UCEC	RPS29P32 →	+0.617	+3.014	<.001	<.001	3	1
UCEC	RN7SL495P →	+0.098	+3.335	.001	.004	3	1
UCEC	SENP3-EIF4A1 →	+0.151	+2.764	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 609 associations by consensus.

ZNF280B by GLIPR2 expression — UCEC

Explore this box plot interactively →