GLCCI1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GLCCI1 mutation is significantly associated with the RNA expression of many other genes, with 2,477 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLCCI1-associated genes across cancer lineages are RNU6-17P, LINC02340, and RN7SL478P. Each is linked with GLCCI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLCCI1-to-partner and partner-to-GLCCI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-17P grouped by GLCCI1-low versus GLCCI1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLCCI1→partner) and Y-score (partner→GLCCI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU6-17P →+0.276+6.018<.001.00233
UCECLINC02340 →+0.404+1.727<.001.00332
UCECRN7SL478P →+0.160+1.643.002.00332
COADSAA3P →+0.139+5.145<.001.00732
UCECUBE2I →+0.333+1.960<.001<.00132
UCECPIAS4 →+0.403+4.031<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,477 associations by consensus.

RNU6-17P by GLCCI1 expression — BLCA

Box plot of RNU6-17P in GLCCI1-low vs GLCCI1-high samples in BLCA.

Explore this box plot interactively →

Exploration