GK5

Across TCGA patient cohorts, GK5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,409 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GK5-associated proteins across cancer lineages are MTA1_S576, DMXL2, and ZNF326. Each is linked with GK5 in more than 4 cancer types. Because this analysis shows association rather than direction, both GK5-to-partner and partner-to-GK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GK5 versus MTA1_S576 in LSCC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GK5→partner) and Y-score (partner→GK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MTA1_S576 →	+0.684	+0.623	.001	.004	3	5
PDAC	DMXL2 →	-0.227	-0.341	.001	<.001	3	4
HNSC	ZNF326 →	+0.478	+0.784	<.001	<.001	3	4
LSCC	PSMB10 →	-0.389	-0.568	<.001	<.001	3	4
LSCC	THEMIS2 →	-0.625	-0.720	<.001	<.001	3	4
LSCC	TOPBP1 →	+0.360	+0.704	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,409 associations by consensus.

GK5 vs MTA1_S576 — LSCC

Explore this scatter interactively →