GJA10

Across TCGA patient cohorts, GJA10 mutation is significantly associated with the RNA expression of many other genes, with 3,705 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GJA10-associated genes across cancer lineages are MIR648, MYO19, and RPIAP1. Each is linked with GJA10 in more than 2 cancer types. Because this analysis shows association rather than direction, both GJA10-to-partner and partner-to-GJA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR648 grouped by GJA10-low versus GJA10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA10→partner) and Y-score (partner→GJA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR648 →	+0.610	+5.060	<.001	.001	3	3
UCEC	MYO19 →	+0.519	+2.263	<.001	<.001	3	3
HNSC	RPIAP1 →	+0.048	+4.163	.004	.001	3	3
LUSC	CENPNP1 →	+0.056	+2.491	<.001	.007	3	3
UCEC	SKA1 →	+0.764	+2.654	<.001	<.001	3	3
UCEC	KIFC1 →	+0.695	+2.643	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,705 associations by consensus.

MIR648 by GJA10 expression — CESC

Explore this box plot interactively →