GINS4

Across TCGA patient cohorts, GINS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,343 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GINS4-associated proteins across cancer lineages are CDK1, DHFR, and SMC2. Each is linked with GINS4 in more than 9 cancer types. Because this analysis shows association rather than direction, both GINS4-to-partner and partner-to-GINS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GINS4 versus CDK1 in LUAD, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS4→partner) and Y-score (partner→GINS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDK1 →	+0.802	+0.746	<.001	<.001	3	10
GBM	DHFR →	+0.652	+0.466	<.001	<.001	3	10
UCEC	SMC2 →	+0.707	+0.923	<.001	<.001	3	10
UCEC	SMC4 →	+0.671	+0.973	<.001	<.001	3	10
BRCA	KPNA2 →	+0.628	+0.615	<.001	<.001	3	10
UCEC	LIG1 →	+0.458	+0.919	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,343 associations by consensus.

GINS4 vs CDK1 — LUAD

Explore this scatter interactively →