GINM1

Across TCGA patient cohorts, GINM1 mutation is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GINM1-associated genes across cancer lineages are RNU6-42P, SNORA10B, and RNU6-342P. Each is linked with GINM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GINM1-to-partner and partner-to-GINM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-42P grouped by GINM1-low versus GINM1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GINM1→partner) and Y-score (partner→GINM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-42P →	+0.472	+3.029	<.001	.009	3	2
BLCA	SNORA10B →	+0.304	+3.472	.006	.003	3	2
UCEC	RNU6-342P →	+0.333	+2.611	.001	.009	3	2
UCEC	LINC01289 →	+0.067	+2.428	.009	.006	3	2
LUAD	OR1E2 →	+0.110	+6.087	<.001	.002	3	1
LUAD	RNU6-997P →	+0.605	+6.444	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

RNU6-42P by GINM1 expression — BLCA

Explore this box plot interactively →