GIMAP1-GIMAP5

Across TCGA patient cohorts, GIMAP1-GIMAP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,348 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible GIMAP1-GIMAP5-associated GO terms across cancer lineages are Regulation of lipopolysaccharide-mediated signaling pathway, Interleukin-12 production, and Blood vessel maturation. Each is linked with GIMAP1-GIMAP5 in more than 10 cancer types. Because this analysis shows association rather than direction, both GIMAP1-GIMAP5-to-partner and partner-to-GIMAP1-GIMAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lipopolysaccharide-mediated signaling pathway grouped by GIMAP1-GIMAP5-low versus GIMAP1-GIMAP5-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP1-GIMAP5→partner) and Y-score (partner→GIMAP1-GIMAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Regulation of lipopolysaccharide-mediated signaling pathway →	+0.137	+1.479	<.001	<.001	3	11
SCLC	Interleukin-12 production →	+0.128	+1.295	<.001	<.001	3	11
SCLC	Blood vessel maturation →	+0.290	+1.827	.002	<.001	3	10
SCLC	Cellular extravasation →	+0.130	+1.484	<.001	<.001	3	10
SCLC	Endothelium development →	+0.087	+1.246	<.001	<.001	3	9
SCLC	Lipopolysaccharide-mediated signaling pathway →	+0.123	+1.595	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,348 associations by consensus.

Regulation of lipopolysaccharide-mediated signaling pathway by GIMAP1-GIMAP5 expression — SCLC

Explore this box plot interactively →