GIMAP1-GIMAP5

Across TCGA patient cohorts, GIMAP1-GIMAP5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,485 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GIMAP1-GIMAP5-associated genes across cancer lineages are CD247, NCR3, and SLA2. Each is linked with GIMAP1-GIMAP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both GIMAP1-GIMAP5-to-partner and partner-to-GIMAP1-GIMAP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIMAP1-GIMAP5 versus CD247 in LUAD, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP1-GIMAP5→partner) and Y-score (partner→GIMAP1-GIMAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD247 →	+1.324	+0.828	.006	.003	3	3
LUAD	NCR3 →	+0.872	+0.845	.001	.002	3	3
LSCC	SLA2 →	+1.098	+0.568	<.001	.001	3	2
LSCC	PPP1R16B →	+1.505	+0.585	<.001	<.001	3	2
LUAD	RASAL3 →	+1.227	+0.884	.007	.001	3	2
LUAD	RASSF4 →	+1.241	+0.904	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,485 associations by consensus.

GIMAP1-GIMAP5 vs CD247 — LUAD

Explore this scatter interactively →