GID4

Across TCGA patient cohorts, GID4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,823 significant associations in total. OV shows the largest number of these associations.

The most reproducible GID4-associated genes across cancer lineages are PIP5K1B, PIK3R3, and LGALSL. Each is linked with GID4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GID4-to-partner and partner-to-GID4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GID4 versus PIP5K1B in HNSC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GID4→partner) and Y-score (partner→GID4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PIP5K1B →	-0.837	-0.338	<.001	<.001	3	2
BRCA	PIK3R3 →	-0.858	-0.356	<.001	<.001	3	2
LSCC	LGALSL →	+0.727	+0.214	<.001	<.001	3	2
HNSC	EAF2 →	-0.547	-0.223	.004	<.001	3	2
HNSC	TXNDC11 →	-0.421	-0.288	.002	.004	3	2
BRCA	SLC37A1 →	-0.606	-0.205	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,823 associations by consensus.

GID4 vs PIP5K1B — HNSC

Explore this scatter interactively →