GHR

Across TCGA patient cohorts, GHR RNA expression is significantly associated with the RNA expression of many other genes, with 19,121 significant associations in total. THYM shows the largest number of these associations.

The most reproducible GHR-associated genes across cancer lineages are C5orf51, CENPC, and SESN3. Each is linked with GHR in more than 30 cancer types. Because this analysis shows association rather than direction, both GHR-to-partner and partner-to-GHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHR versus C5orf51 in THYM, with a Pearson correlation of 0.63.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GHR→partner) and Y-score (partner→GHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	C5orf51 →	+1.092	+1.814	<.001	<.001	3	31
UVM	CENPC →	+0.784	+0.381	<.001	<.001	3	30
ESCA	SESN3 →	+1.753	+1.213	<.001	<.001	3	30
UVM	PHC3 →	+0.907	+0.502	<.001	<.001	3	30
THYM	MEF2A →	+1.407	+1.578	<.001	<.001	3	30
THYM	KLHL20 →	+1.166	+1.452	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,121 associations by consensus.

GHR vs C5orf51 — THYM

Explore this scatter interactively →