GHR

Across TCGA patient cohorts, GHR RNA expression is significantly associated with the protein abundance of many other proteins, with 17,545 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GHR-associated proteins across cancer lineages are SORBS3, TLN2, and FERMT2. Each is linked with GHR in more than 7 cancer types. Because this analysis shows association rather than direction, both GHR-to-partner and partner-to-GHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHR versus SORBS3 in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GHR→partner) and Y-score (partner→GHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SORBS3 →	+0.574	+0.692	<.001	<.001	3	8
OV	TLN2 →	+0.628	+0.927	<.001	<.001	3	8
BRCA	FERMT2 →	+0.743	+1.499	<.001	<.001	3	8
COAD	PRELP →	+1.017	+0.736	<.001	<.001	3	7
UCEC	PRKG1 →	+0.761	+0.725	<.001	<.001	3	7
HNSC	RAI14 →	+0.438	+0.955	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,545 associations by consensus.

GHR vs SORBS3 — UCEC

Explore this scatter interactively →