GHITM

Across TCGA patient cohorts, GHITM protein abundance is significantly associated with the RNA expression of many other genes, with 9,942 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GHITM-associated genes across cancer lineages are ZNF699, ZNF430, and GLIS2. Each is linked with GHITM in more than 4 cancer types. Because this analysis shows association rather than direction, both GHITM-to-partner and partner-to-GHITM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHITM versus ZNF699 in OV, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GHITM→partner) and Y-score (partner→GHITM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF699 →	-0.501	-0.532	.003	.001	3	5
OV	ZNF430 →	-0.527	-0.507	<.001	.002	3	4
OV	GLIS2 →	-0.789	-0.378	.004	.003	3	4
GBM	RBMS1 →	-0.581	-0.404	<.001	.001	3	4
LUAD	STARD9 →	-0.588	-0.723	.001	.004	3	4
LSCC	VDAC2 →	+0.749	+0.362	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,942 associations by consensus.

GHITM vs ZNF699 — OV

Explore this scatter interactively →