GHET1

Across TCGA patient cohorts, GHET1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,797 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GHET1-associated proteins across cancer lineages are ARHGAP25_S512, TOP2A_S1377, and CDK5. Each is linked with GHET1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GHET1-to-partner and partner-to-GHET1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHET1 versus ARHGAP25_S512 in LSCC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GHET1→partner) and Y-score (partner→GHET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP25_S512 →	-0.696	-0.495	<.001	<.001	3	4
LSCC	TOP2A_S1377 →	+0.730	+0.349	<.001	<.001	3	4
OV	CDK5 →	+0.355	+0.449	.004	.001	3	4
OV	GPRIN1_S615 →	+0.996	+0.611	.004	.002	3	4
LSCC	GTF2I →	+0.525	+0.487	<.001	<.001	3	4
OV	RHEB →	+0.469	+0.544	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,797 associations by consensus.

GHET1 vs ARHGAP25_S512 — LSCC

Explore this scatter interactively →