GHET1

Across TCGA pan-cancer cohorts, GHET1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated GHET1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher GHET1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GHET1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and OV show a favorable association.

KIRP, KIRC, and OV are the cancer types where GHET1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	All	0.531	0.753	<.001	48	view →
KIRC	DFS	Median	All	0.744	0.492	<.001	40	view →
OV	OS	Median	IV	0.812	0.463	<.001	30	view →
LIHC	OS	Median	All	0.693	0.859	<.001	29	view →
UVM	DFS	Median	III,IV	0.208	0.740	.006	28	view →
MESO	DFS	Median	III,IV	0.203	0.632	.001	27	view →
UCS	DFS	Tertile	IV	0.932	0.484	.024	24	view →
BRCA	DFS	Median	IV	0.900	0.505	.010	18	view →
ACC	DFS	Quartile	III,IV	0.440	0.072	.019	18	view →
THCA	DFS	Tertile	III,IV	0.525	0.885	.020	9	view →
BLCA	OS	Tertile	All	0.486	0.688	.040	7	view →
LGG	DFS	Quartile	All	0.514	0.303	.007	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

GHET1–KIRP (DFS)

Open the KIRP breakdown →