GGT6

Across TCGA patient cohorts, GGT6 mutation is significantly associated with the RNA expression of many other genes, with 514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GGT6-associated genes across cancer lineages are PANK4, ZNF57, and COX10. Each is linked with GGT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGT6-to-partner and partner-to-GGT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PANK4 grouped by GGT6-low versus GGT6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT6→partner) and Y-score (partner→GGT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PANK4 →	+0.416	+3.384	.004	.004	3	2
UCEC	ZNF57 →	+0.452	+3.258	<.001	<.001	3	2
UCEC	COX10 →	+0.447	+3.595	<.001	.001	3	2
UCEC	COASY →	+0.492	+2.606	<.001	<.001	3	2
UCEC	HMOX2 →	+0.345	+3.656	.006	.001	3	2
UCEC	HPS1 →	+0.405	+2.584	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

PANK4 by GGT6 expression — SKCM

Explore this box plot interactively →